TKB245 is a highly potent SARS-CoV-2 Mpro inhibitor that effectively blocks SARS-CoV-2 replication in VeroE6 cells[1].
References
[1] Kohei Tsuji, et al. Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties. J Med Chem. 2023 Oct 12;66(19):13516-13529. DOI:10.1021/acs.jmedchem.3c00777
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