4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺
![4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 结构式](https://img.chemicalbook.com/CAS/20200611/GIF/97919-22-7.gif)
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 性质
熔点 | >197°C (dec.) |
---|---|
密度 | 1.4254 (rough estimate) |
折射率 | 1.5630 (estimate) |
储存条件 | Refrigerator |
溶解度 | 可溶于DMSO(少许)、甲醇(少许) |
形态 | 固体 |
颜色 | 浅棕色至棕色 |
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 用途与合成方法
topoisomerase II alpha
|
topoisomerase II beta
|
The Chloroquinoxaline sulfonamide IC
50
for CV-1cells, obtained using an MTT cytotoxicity assay, was 1.8 mM. Chloroquinoxaline sulfonamide causes dose-dependent protein-DNA cross-links to CV-1 monkey kidney cell chromosomal DNA when drug treatment was terminated by lysis with GuHCl. Chloroquinoxaline sulfonamide-induced protein-DNA cross-links in CV-1 cells. Chloroquinoxaline sulfonamide-induced topoisomerase II-DNA cross-links.
Chloroquinoxaline sulfonamide (Chloroquinoxaline), a chlorinated derivative of sulfaquinoxaline, inhibits proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) are used.
Cell Proliferation Assay
Cell Line: | B16 murine melanoma cells |
Concentration: | 10 μM, 100 μM, 1 mM |
Incubation Time: | 24, 48, 72 hours |
Result: | Inhibited proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) were used. |
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-04-30 | HY-106662 | 1 mg | 750 | ||
2024-04-30 | HY-106662 | 4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 | 97919-22-7 | 5mg | 1650 |