4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 性质
| 熔点 | >197°C (dec.) |
|---|---|
| 密度 | 1.4254 (rough estimate) |
| 折射率 | 1.5630 (estimate) |
| 储存条件 | Refrigerator |
| 溶解度 | 可溶于DMSO（少许）、甲醇（少许） |
| 形态 | 固体 |
| 颜色 | 浅棕色至棕色 |
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 用途与合成方法
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topoisomerase II alpha
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topoisomerase II beta
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The Chloroquinoxaline sulfonamide IC
50
for CV-1cells, obtained using an MTT cytotoxicity assay, was 1.8 mM. Chloroquinoxaline sulfonamide causes dose-dependent protein-DNA cross-links to CV-1 monkey kidney cell chromosomal DNA when drug treatment was terminated by lysis with GuHCl. Chloroquinoxaline sulfonamide-induced protein-DNA cross-links in CV-1 cells. Chloroquinoxaline sulfonamide-induced topoisomerase II-DNA cross-links.
Chloroquinoxaline sulfonamide (Chloroquinoxaline), a chlorinated derivative of sulfaquinoxaline, inhibits proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) are used.
Cell Proliferation Assay
| Cell Line: | B16 murine melanoma cells |
| Concentration: | 10 μM, 100 μM, 1 mM |
| Incubation Time: | 24, 48, 72 hours |
| Result: | Inhibited proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) were used. |
4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-106662R | 4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 | 97919-22-7 | 1 mg | 1440 |
| 2026-09-15 | HY-106662R | 4-氨基-N-(5-氯-2-喹喔啉)苯磺酰胺 | 97919-22-7 | 5 mg | 3690 |
