Hexadecylphosphoserine is a growth inhibitory representative.
Hexadecylphosphoserine is a phospholipid molecule that contains a long-chain alkyl (hexadecyl) and a phosphoserine group, giving it a high affinity for the cell membrane. Hexadecylphosphoserine can exert antitumor activity by modulating [Ca++]i and its related signaling pathways, making it useful for research in the field of breast cancer[1].
[1] Bergmann J, et al. Multiple effects of antitumor alkyl-lysophospholipid analogs on the cytosolic free Ca2+ concentration in a normal and a breast cancer cell line. Anticancer Res. 1994 Jul-Aug;14(4A):1549-56. PMID:7979184
