占托西林 性质
| 沸点 | 430.53°C (rough estimate) |
|---|---|
| 密度 | 1.2396 (rough estimate) |
| 折射率 | 1.5800 (estimate) |
| 酸度系数(pKa) | 9.013±0.26(predicted) |
占托西林 用途与合成方法
Xanthocillin 是从青霉中提取的一种海洋药剂，通过抑制 MEK/ERK 途径诱导自噬。
Xantocillin (SD118-xanthocillin X (1)) (6.9-55.56 µM; 48 hours) has a significant inhibitory effect on the proliferation of HepG2 cells with an IC
50
of 22.88 ± 4.76 µM.
Xantocillin (SD118-xanthocillin X (1)) (24.3 µM; 12-48 hours) increases the expression of the autophagy-related genes, LC3, and Beclin 1.
Cell Proliferation Assay
| Cell Line: | HepG2 cells |
| Concentration: | 6.9 µM, 13.89 µM, 27.78 µM, 55.56 µM |
| Incubation Time: | 48 hours |
| Result: | A concentration-dependent inhibitory effect on cellular growth in the HepG2 cells with the IC 50 of 22.88 ± 4.76 µM. |
Western Blot Analysis
| Cell Line: | HepG2 cells |
| Concentration: | 24.3 µM |
| Incubation Time: | 12 hours, 24 hours, 48 hours |
| Result: | Increased the expression of the autophagy-related genes, LC3, and Beclin 1. |
占托西林供应商 更多
TargetMol中国（陶术生物）
联系电话：4008200310 15002144251
产品介绍：
中文名称：黄青霉素
英文名称：Xantocillin
CAS：580-74-5
包装信息：25mg
