Β-AMINOARTEETHER
中文名称:Β-AMINOARTEETHER
英文名称:Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]-
CAS号:133162-24-0
分子式:C17H29NO5
分子量:327.42
EINECS号:
Mol文件:133162-24-0.mol
![Β-AMINOARTEETHER 结构式](https://img.chemicalbook.com/CAS/20210111/GIF/133162-24-0.gif)
Β-AMINOARTEETHER 性质
沸点 | 421.0±45.0 °C(Predicted) |
---|---|
密度 | 1.20±0.1 g/cm3(Predicted) |
酸度系数(pKa) | 8.46±0.10(Predicted) |
Β-AMINOARTEETHER 用途与合成方法
β-Aminoarteether (SM934 free base) 是一种具有口服活性的 Artemisinin 衍生物。β-Aminoarteether 可用于炎症和自身免疫性疾病的研究,例如狼疮疾病。
β-Aminoarteether (SM934;10 µM; 24 hours) treatment directly enhances IL-10 production and suppresses IL-12/23p40 production in primary peritoneal macrophages with IFN-γ stimulation.
In vitro, β-Aminoarteether (SM934) could suppress the Th1 and Th17 polarization, but exerted no influence on Treg differentiation.
β-Aminoarteether (SM934; 1-10 mg/kg; oral administration; daliy; for 3 months) treatment significantly delays the progression of glomerulonephritis and increases the survival rate of NZB/W F1 mice. β-Aminoarteether treatment promots the IL-10 production of macrophages from NZB/W F1 mice.
Animal Model: | Female NZB/W F1 mice (Six and half months old) |
Dosage: | 1 mg/kg, 3 mg/kg, and 10 mg/kg |
Administration: | Oral administration; daliy; for 3 months |
Result: | Significantly delayed the progression of glomerulonephritis and increased the survival rate of NZB/W F1 mice. |
Β-AMINOARTEETHER供应商 更多
上海源溪生物科技有限公司
联系电话:021-58447131 13564518121
产品介绍:
英文名称:β-Aminoarteether
CAS:133162-24-0
纯度:98% HPLC
包装信息:100mg,250mg,1g
天津普西唐生物医药科技有限公司
联系电话:010-60605840 15801484223;
产品介绍:
英文名称:β-Aminoarteether
CAS:133162-24-0
包装信息:1g
备注: 试剂级
TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物β-Aminoarteether
英文名称:β-Aminoarteether
CAS:133162-24-0
纯度:97.02%
包装信息:1 mg;10 mg;100 mg;25 mg;5 mg;50 mg
銳迪國際科技有限公司
联系电话: 18024082417
产品介绍:
英文名称:β-Aminoarteether
CAS:133162-24-0
纯度:5mg;10mg;50mg;100mg;250mg;500mg;1g
包装信息:5mg;10mg;50mg;100mg;250mg;500mg;1g