Dalbavancin hydrochloride

Chemical Properties

storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO: ≥ 24 mg/mL (12.95 mM)
Water Solubility	Water: 50 mg/mL (26.98 mM)

Animal Model:	Female BALB/c mice (6-8 weeks) challenged with Ames strain of B . anthracis
Dosage:	15 mg/kg, 30 mg/kg, 60 mg/kg, 120 mg/kg, 240 mg/kg
Administration:	Intraperitoneal injection ; every 36 h or 72 h; for 14 days
Result:	The efficacy was 80 to 100%, as determined by the rate of survival at 42 days, when treatment was initiated 24 h postchallenge with regimens of 15 to 120 mg/kg every 36 h or 30 to 240 mg/kg every 72 h.