ARG--TYR--LEU--PRO-THR
ARG--TYR--LEU--PRO-THR 性质
| 密度 | 1.43±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | Store at -20°C |
| 酸度系数(pKa) | 3.28±0.10(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
ARG--TYR--LEU--PRO-THR 用途与合成方法
Proctolin can increase the frequency of action potentials, increase the amplitude of muscle contraction, and initiate activity in quiescent systems. In the arthropods, Proctolin acts as a neuromodulator and possibly as a neurohormone. It does not appear to function as a conventional neurotransmitter. Proctolin is a pentapeptide with the mature peptide of RYLPT, and it is the first insect neuropeptide to be sequenced and chemically characterized. The first identification of a Proctolin precursor gene is CG7105 in D. melanogaster . Although a previous study showed that Proctolin is absent in B. mori , this pentapeptide is recently identified in a proteomic analysis of B. mori wings. However, the Bombyx Proctolin gene does not produce a mature peptide because cleavage sites are not present at the N-terminal and C-terminal of the RYLPT sequence, and a similar gene is observed in C. suppressalis . Therefore, a true Proctolin has been considered to be not observed in B. mori and C. suppressalis .
