In exometabolome analysis using 1H-NMR (nuclear magnetic resonance) spectroscopy, 3-(Trimethylsilyl)-1-propanesulfonic acid-d6 sodium salt has been used as an internal standard for metabolite quantification. It has been used for the preparation of DMSO (dimethyl sulfoxide)/DSS solvent solution to make NMR leaf extract samples.
3-(Trimethylsilyl)-1-propanesulfonic acid (also referred to as DSS (2,2-Dimethyl-2-silapentane-5-sulfonate)) is an internal standard for NMR (nuclear magnetic resonance) studies. It results in high intensity proton peaks which are easily identified. DSS also has negligible sensitivity towards pH and temperature changes.