[5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone

Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor[1].

Topoisomerase I; Topoisomerase II

[1] Ahmad P, et al. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure–activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor[J]. Bioorganic & Medicinal Chemistry, 2016, 24(8): 1898-1908. DOI:10.1016/j.bmc.2016.03.017