N-(3-Oxobutanoyl)-L-homoserine lactone

Product NameN-(3-Oxobutanoyl)-L-homoserine lactone
CAS148433-27-6
MFC8H11NO4
MW185.18
EINECS
MOL File148433-27-6.mol

Chemical Properties

storage temp.	Store at -20°C
solubility	Chloroform: Soluble
form	A solid

Usage And Synthesis

Uses

N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum[1].

Definition

ChEBI: N-(3-oxo-butanoyl)-homoserine lactone is a N-acyl-amino acid.

Biological Activity

N-3-oxo-butyryl-L-Homoserine lactone is a bacterial quorum-sensing signaling molecule.1 It induces expression of rhiI in R. leguminosarum, a gene with roles in the interaction of the rhizosphere with legumes.

References

1.Rodelas, B., Lithgow, J.K., Wisniewski-Dye, F., et al.Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciaeJ. Bacteriol.181(12)3816-3823(1999)