Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III[1].
in vivo
In Syrian hamster bearing natural rabies virus, Foravirumab (CR4098; 10, 20, and 40 IU/kg) provids protection against the lethal natural rabies virus infection[1].
References
[1] Alexander B H Bakker, et al. Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants. J Virol. 2005 Jul;79(14):9062-8. DOI:10.1128/JVI.79.14.9062-9068.2005
