Oligomycin E is a minor metabolite of the oligomycin complex produced by several species of Streptomyces. It exhibits relatively weak antifungal activity compared to other oligomycins, yet is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14 ng/ml).
Oligomycin E is a minor metabolite from the oligomycin complex with weak antibacterial and antifungal activity.
Oligomycin E (26-hydroxyoligomycin B) is a minor metabolite from the oligomycin complex produced by several species of Streptomyces. Unlike the other oligomycins, oligomycin E exhibits weak antibacterial activity and is considerably weaker as an antifungal agent.
[1] K KOBAYASHI. Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225.[J]. Journal of Antibiotics, 1987, 40 7: 1053-1057. DOI:
10.7164/antibiotics.40.1053
