MRS2603 is a P2Y1 and P2Y13 receptors antagonist expressed in 1321N1 human astrocytoma cells.
MRS2603 is a pyridoxal derivative. MRS2603 antagonized both P2Y1 and P2Y13 receptors[1].
P2Y1 Receptor; P2Y13 Receptor
[1] Kim YC, et al. Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor. Biochem Pharmacol. 2005 Jul 15;70(2):266-74. DOI:
10.1016/j.bcp.2005.04.021
