[1-(3-methylbutan-2-yl)indol-3-yl]-naphthalen-1-ylmethanone

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB₁ and peripheral CB₂ receptors (K_i = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 018 N-(1,2-dimethylpropyl) isomer differs from JWH 018 structurally by having a 1,2-dimethylpropyl chain, rather than a pentyl chain, extending from the indole group. The biological activities of this compound have not been characterized. This product is intended for forensic purposes.

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