Fasudil Impurity 13

Isoquinoline-8-sulfonyl Chloride can be useful in the synthesis and biological evaluation of N-??(3-??oxo-??3,??4-??dihydro-??2H-??benzo[b]??[1,??4]??oxazin-??7-??yl)??benzenesulfonamide derivatives as new BET bromodomain inhibitors for anti-??hematologic malignancies activities.