Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone

A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICE_rel-III, TY), as well as caspase-1 and caspase-4.
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.

Caspase-5 inhibitor. Inhibits ECyd-induced rRNA fragmentation in mouse mammary tumor and human fibrosarcoma cells.