GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2
GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 性质
| 沸点 | 1697.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.337±0.06 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | H2O：12.5 mg/mL（11.04 mM；需要超声波） |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.16±0.46(Predicted) |
| 水溶解性 | Soluble to 1 mg/ml in water |
| 序列 | H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2 |
GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 用途与合成方法
|
Human Endogenous Metabolite
|
Potency to stimulate contraction of rat uterine smooth muscle, that is used as bioassay for isolation of Neuromedin B (NMB), is compared with Bombesin (BN). The relative potency, calculated on molar basis by taking BN as 100, is 48% for GRP and 4.9% for NMB. NMB also has contractile activity on rat stomach strip, but the potency (ratio of peptide concentration required to elicit 50% maximum response; EC 50 ) is only 5% of BN (EC 50 of BN/EC 50 of NMB) and about 10% of GRP (EC 50 of GRP/ EC 50 of NMB).
Potencies of NMB and GRP for smooth muscle contraction of fundus in wild-type and NMB-R-deficient mice with ED 50 of 14.4±2.3 (n=8) and 10.9±2.3 (n=8) in wild-type mice and NMB-R-deficient mice, respectively.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-01-25 | HY-P0241 | GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 | 87096-84-2 | 1mg | 800 |
| 2024-01-25 | HY-P0241 | GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 | 87096-84-2 | 5mg | 3100 |
