Anti-solute carrier family 39 (zinc transporter), member 6

Anti-SLC39A6 polyclonal antibody is used to tag solute carrier family 39 (Zinc transporter), member 6/zinc transporter 6 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 39 (Zinc transporter), member 6/zinc transporter 6 in intracellular zinc homeostasis, epithelial-to-mesenchymal transition (EMT) in cancer cells, and in HDACi-induced apoptosis.

ZIP6 (ZIP metal ion transporter family) controls the expression level of E-cadherin. It serves as a zinc influx transporter. SLC39A6 participates in the cellular invasion of HeLa cells by modulating the snail and slug expression mediated by ERK (extracellular signal–regulated kinase).