Fusarisetin A is a pentacyclic fungal metabolite first isolated from Fusarium species. At 3-30 μg/ml, it is reported to inhibit acinar morphogenesis, cell migration, and invasion in a 3D-matrigel assay system designed to study tumor cell motility.
Fusarisetin A is an unusual pentacyclic metabolite and an inhibitor of acini.
Fusarisetin is an unusual pentacyclic metabolite related to equisetin and isolated from a Fusarium. Fusarisetin was identified from a natural product screen using a three-dimensional matrigel-induced bioassay to study acinar morphogenesis. Fusarisetin is the first inhibitor of acini reported in the literature.
