4-[1-(Cyclohexyl-d11)-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-2-pyriMidinaMine Dihydrochloride
4-[1-(Cyclohexyl-d11)-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-2-pyriMidinaMine Dihydrochloride
英文名称:4-[1-(Cyclohexyl-d11)-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-2-pyriMidinaMine Dihydrochloride
CAS号:
分子式:C19H11Cl2D11FN5
分子量:421.383662758
EINECS号:
Mol文件:Mol File
4-[1-(Cyclohexyl-d11)-4-(4-fluorophenyl)-1H-iMidazol-5-yl]-2-pyriMidinaMine Dihydrochloride 用途与合成方法
用途
Labelled analogue of PF 670462, a potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor. PF 670462 has been shown to inhibit PER protein nuclear translocation causing phase shifts in circadi an rhythms. PF 670462 attenuates methamphetamine-stimulated locomotion in vivo.