The synthesis of nitro acetate: a typical approach is to add conc Nitric Acid (38 mL) slowly to stirred, cooled Acetic Anhydride (150 mL). In the earliest report,2 N2O5 was dissolved in Ac2O; though less practical, this is recommended for preparing anhydrous inorganic nitrates. Other methods involve reaction of HNO3 and ketene, or AcCl and AgNO3 in MeCN in the presence of the substrate to be nitrated.
