L-Phenylalanine, 4-(aminomethyl)-N-[(2R,3S)-3-[(hydroxyamino)carbonyl]-2-(2-methylpropyl)-1-oxo-6-phenylhexyl]-

F81-1144b is a matrix metalloproteinase inhibitor which reduces secretion of very low density lipoprotein-triacylglycerol, thereby lowering TAG levels in serum and the liver. F81-1144b also lowers VLDL-TAG secretion, de novo FA synthesis in the liver, and serum levels of insulin and glucose.