KELATORPHAN
KELATORPHAN 性质
| 密度 | 1.301±0.06 g/cm3(Predicted) |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 酸度系数(pKa) | 3.58±0.10(Predicted) |
| 颜色 | 白色至米白色 |
KELATORPHAN 用途与合成方法
Enkephalin degrading enzyme.
The administration of Kelatorphan alone (50 μg) could result in a strong increase of intact [ 3 H]enkephalin content corresponding to 80±11% of total recovered radioactivity. In normal awake rats, Kelatorphan (10±20 mg/kg i.v.) increases minute-volume. The increase in ventilation is due to a dose-dependent increase in breathing frequency. In arthritic rats Kelatorphan (20 mg/kg i.v.) increases ventilation and there is no significant difference between arthritic and non-arthritic rats. In pentobarbital-anesthetized rats, a slight (116%) but significant increase of respiration is also produced by Kelatorphan (20 mg/kg, n=6) 10±15 min after administration. The effects of Kelatorphan are not antagonized by a pretreatment with a small dose of naloxone (0.2 mg/kg i.v., 15 min before Kelatorphan), but a larger dose (1 mg/kg) significantly antagonized Kelatorphan (20 mg/kg) at 5 and 10 min in awake rats.
KELATORPHAN 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-02-08 | HY-10827 | 92175-57-0 | 1 mg | 2800 | |
| 2025-02-08 | HY-10827 | 92175-57-0 | 10 mM * 1 mLin DMSO | 9064 |
