Myelin/oligodendrocyte glycoprotein (MOG) is a major component of the central nervous system. It is involved in several cellular processes including cellular adhesion, in the regulation of oligodendrocyte microtubule stability and facilitates the interactions between myelin and the immune system. It has been reported th at MOG may be involved in the completion and/or maintenance of the myelin sheath, and in cell-cell communication. It has also been observed th at mutation or polymorphisms in MOG gene could cause multiple sclerosis.
