LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 μM. LEM-14 has the potential for the research of multiple myeloma[1].
References
[1] Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108. DOI:10.1016/j.bbrc.2018.11.037