2,3,7,8-Tetrafluorothianthrene-
S-oxide (TFT
S-oxide) is a fluorinated sulfoxide-based thianthrene reagent for late-stage C-H functionalization. Developed by the
Ritter Lab, C-H functionalization by thianthrenation with TFT
S-oxide proceeds with >99% selectivity and furnishes functionalized arenes serving as synthetic linchpins for further participation in diverse transformations.
The nonfluorinated thianthrene
S-oxide is also available as catalog# 903973 for all arenes more electron-rich than anisole.