(tetrahydro-2H-pyran-4,4-diyl)dimethanamine

[4-(Aminomethyl)oxan-4-yl]methanamine is used as a reactant in the oxidative cyclization of N''-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor antagonists with unique structural features.