Cyanine5.5 DBCO

Product NameCyanine5.5 DBCO
CAS2643308-61-4
MFC61H63F6N4O2P
MW1029.17
EINECS
MOL File2643308-61-4.mol

Chemical Properties

solubility	good in DMF, DMSO, chlorinated organic solvents
form	Solid
color	Purple to purplish red
Appearance	dark colored solid
SMILES	[Cl-].CN1\C(=C\C=C\C=C\C2=[N+](CCCCCC(=O)NCCCCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)c3ccc4ccccc4c3C2(C)C)C(C)(C)c2c1ccc1ccccc21

Usage And Synthesis

Description

Strain promoted alkyne azide cycloaddition (SPAAC) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAC click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

Uses

Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging[1].

References

[1] Yong Geun Lim, et al. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry. Volume 89, 25 September 2020, Pages 442-447

Abs/Em Maxima

684/710 nm

Fluoresene quantum yield

0.2

Extinction Coefficient

198000