[Orn8]-Urotensin II (human) (trifluoroacetate salt)

[Orn8]-Urotensin II is a peptide analog of urotensin II (Item No. 24711) and agonist of the urotensin II receptor (UTR; EC50s = 11.74 and 8.7 nM in HEK293 cells expressing the human and rat receptor, respectively).1 It reduces urotensin II-induced contraction of isolated rat aorta (pA2 = 6.56) but has no effect on aortic contraction when used alone at concentrations up to 10 μM.WARNING This product is not for human or veterinary use.

[1] VALERIA CAMARDA. A new ligand for the urotensin II receptor[J]. British Journal of Pharmacology, 2009, 137 3: 311-314. DOI: 10.1038/sj.bjp.0704895