IITZ-01 (45 mg/kg, ip every alternate day for 4 weeks) inhibits average breast tumor growth when compared with control from third day of treatment in triple-negative breast tumor models in mice.
Animal Model: | MDA-MB-231 (TNBC)/green fluorescent protein (GFP) orthotropic breast cancer xenografts were developed in CrTac:NCr- Foxn nu BALB/c female nude mice. |
Dosage: | 45 mg/kg. |
Administration: | Intraperitoneal every alternate day for 4 weeks. |
Result: | Inhibited average breast tumor growth when compared with control from third day of treatment. |