Monoclonal Anti-Collagen, Type I antibody produced in mouse has been used in:
immunohistochemistry
dot blot technique
indirect immunofluorescence staining
General Description
Collagen type I contributes maximum to the fibrous protein content in mammals. It is also present in arteries and extracellular matrix. The protein has an elongated cylindrical structure with tapering ends. It possess a left-handed helix with three polyproline II-type polypeptide strands.
Biochem/physiol Actions
Collagen type I is responsible for mechanical stability, elasticity, strength and toughness, observed in tendons, ligaments, skin, cornea, bone, dentin and many other tissues.