NNMT-IN-7 (Compound 4e) is a NNMT inhibitor (IC50 = 505.7 μM). NNMT-IN-7 can be used in studies of metabolic and chronic diseases[1].
IC 50
NNMT: 505.7 μM (IC50)
References
[1] Neelakantan H, et al. Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase. J Med Chem. 2017 Jun 22;60(12):5015-5028. DOI:10.1021/acs.jmedchem.7b00389
