Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1].
in vivo
Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice[1].
Animal Model:
Tumor targeted pro-apoptotic peptide (250 μg/mice; tail vein injection; 250 μg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice[1].
Dosage:
250 μg/mice
Administration:
Tail vein injection; 250 μg a week for 17 weeks
Result:
Exhibited antitumor activity in vivo.
References
[1] Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5(9):1032-8. DOI:10.1038/12469
