5-cis-15(R)-Iloprost

5-cis-15(R)-Iloprost is the C-5 cis-isomer and 15(R)-epimer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 5-cis-15(R)-iloprost.WARNING This product is not for human or veterinary use.

[1] K SCHRÖR. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK 36 374)–equipotent to PGI2 in vitro.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1981, 316 3: 252-255. DOI: 10.1007/bf00505658