3,5,7-Trimethoxyflavone, a flavonoid compound, can inhibit the TNF-α-induced high expression and secretion of MMP-1 by cells. 3,5,7-Trimethoxyflavone can be used to ameliorate skin damage[1].
Definition
ChEBI: A trimethoxyflavone that is the 3,5,7-trimethyl ether derivative of galangin.
References
[1] Lee S, et, al. Improvement of Damage in Human Dermal Fibroblasts by 3,5,7-Trimethoxyflavone from Black Ginger ( Kaempferia parviflora). Antioxidants (Basel). 2022 Feb 19;11(2):425. DOI:10.3390/antiox11020425