(7S)-6,7-Dihydro-7-[[(2-hydroxyphenyl)methyl]methylamino]-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one

An alkaloid found in Colchicum speciosum Stev., the base yields prismatic yellow crystals from a mixture of C6H6 and Me2CO. It has [α]²⁰_D- 21.2° (c 1.752, CHCI3). Four methoxyl groups and one phenolic hydroxyl group are present, the structure given above having been confirmed by synthesis.

Kise1ev.,J. Gen. Chem., USSR, 26,3218 (1956)
Synthesis: Barker et ai., Chem. Commun., 390 (1967)