KF31327
KF31327 用途与合成方法
|
PDE5 0.074 nM (IC 50 ) |
PDE1 380 nM (IC 50 ) |
PDE2 670 nM (IC 50 ) |
PDE3 38 nM (IC 50 ) |
PDE4 800 nM (IC 50 ) |
Thioquinapiperifil can be found in dietary supplements.
Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation.
Thioquinapiperifil (KF31327 free base) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil (KF31327)-treated cells is 0.95±0.17 pmol/10
8
cells.
