Caveolin-1 (82-101) amide is a 20-amino acid synthetic peptide fragment corresponding to residues 82-101 of caveolin-1, which is involved in endocytosis and interacts with a variety of receptors and other proteins.1 Caveolin-1 (82-101) (0.8 µmol/kg) reduces aging-induced increases in microvascular leakage and fibrosis, as well as the ratio of phosphorylated-to-unphosphorylated PDGFR and protein-rich tyrosine 2 (Pyk2), in aged mouse heart, kidney, and brain. It also increases left ventricular ejection fraction and fractional shortening and reduces aging-induced isovolumic relaxation time (IVRT) and cardiac hypertrophy in aged mice.WARNING This product is not for human or veterinary use.
