White or off-white crystalline powder (methanol), odorless and tasteless. Melting point 249-254°C. Soluble in chloroform, soluble in acetone, slightly soluble in anhydrous ethanol, insoluble in water.
6-epi-Medroxy Progesterone 17-Acetate (Megestrol Acetate EP Impurity F) is the epimer of Medroxyprogesterone acetate (M203560). Progesterone (1) impurity. Induces LEFTY expression in normal endometrium cells (2). As a derivative of Progesterone, it may assist in the modulation of ATP-induced calcium signaling in breast cancer cells (3).