chlorpromazine N-oxide

Chlorpromazine N-Oxide is a metabolite of Chlorpromazine. Chlorpromazine exhibits antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic properties, and commonly used to treat schizophrenia.

ChEBI: An organochlorine compound that is chlorpromazine in which the acyclic tertiary amino group has been converted into the corresponding N-oxide.

When female rats are administered chlorpromazine N- oxide orally, the metabolites identified in both urine and feces are chlorpromazine, 7- hydroxychlorpromazine, chlorpromazine sulfoxide, N- desmethylchlorpromazine and N- desmethylchlorpromazine sulfoxide. Chlorpromazine N-oxide and any metabolite that retains the intact N- oxide function, such as chlorpromazine N,S-dioxide, cannot be identified in any of the extracts.