1H-Indazole-3-carboxamide, N-[1-(aminocarbonyl)-2-methylpropyl]-1-(5-fluoro-4-hydroxypentyl)-

5-fluoro AB-PINACA is a derivative of AB-PINACA , a synthetic cannabinoid recently identified in illegal herbal products.¹ 5-fluoro AB-PINACA N-(4-hydroxypentyl) metabolite is an expected phase 1 metabolite of 5-fluoro AB-PINACA, based on the known metabolism of similar compounds.^2,3 The physiological properties of this compound have not been evaluated. This product is intended for forensic and research applications.

ChEBI: 5-fluoro AB-PINACA N-(4-hydroxypentyl) metabolite is a N-acyl-amino acid.

1. Uchiyama, N., Matsuda, S., Wakana, D., et al. New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products Forensic Toxicol. 31(1),93-100(2013).
2. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB₂) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).