Atto 495 is a new label for proteins and oligo-nucleotides with high molecular absorption (80.000) and quantum yield (0.45) as well as sufficient stoke′s shift (excitation maximum 495 nm, emission maximum 527 nm). Atto 495 is characterized by a high photostability and thermostability. It is slightly hydrophilic, and solubility in polar solvents as DMF or DMSO is high.', 'Atto fluorescent labels are designed for high sensitivity applications, including single molecule detection. Atto labels have rigid structures th at do not show any cis-trans-isomerization. Thus these labels display exceptional intensity with minimal spectral shift on conjugation.