In 1942 phenbenzamine (Antergan), C17H22N2, was the first antihistamine to be successfully used in humans.
ChEBI: Phenbenzamine is an aromatic amine.
Antergan neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.
Poison by subcutaneous,intraperitoneal, and intramuscular routes. When heated todecomposition it emits toxic fumes of NOx.
