Tacrolimus
104987-11-3 Basic informationMore
- Product Name:Tacrolimus
- Synonyms: (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s* ,19s*,26ar*))- 16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- L 679934 FK-506:FR-900506 Fujimycin Prozraf Tacrolimus,micronisedandpharmagrade
- CAS:104987-11-3
- MF:C44H69NO12
- MW:804.02
- EINECS:1308068-626-2
- Mol File:104987-11-3.mol
USE
FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system. Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα.
Lastest Price from Tacrolimus manufacturers
- Tacrolimus
- US $0.00 /Kg/Bag
- CAS:104987-11-3
- Min. Order: 2Kg/Bag
- Purity: USP
- Supply Ability: 20 tons
- 2025-01-26
- Tacrolimus
- US $150.00 /kg
- CAS:104987-11-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500kg
- 2025-01-24
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- Company Name:Sichuan Mingjian Pharmaceutical Chemical Co., Ltd.
- Tel: 15281098982
- Products Intro:Product Name:Tacrolimus
CAS:104987-11-3
Purity:99% Package:1kg/RMB 10 - CB Index:58
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- Company Name:HUBEI MICRO PHARMACEUTICAL
- Tel: 18627055345
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CAS:104987-11-3
Purity:99% Package:10g;100g;1000g - CB Index:58
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- Company Name:Taizhou Hoyoo Chemical Co.,Ltd
- Tel:0576-0576-88666163 15057600339
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CAS:104987-11-3
Purity:98.5% Package:1G 5G 100G 1KG More... - CB Index:58
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- Company Name:Shanghai Zhibang Biological Medicine Co., LTD
- Tel:021-54285032 18116461626
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CAS:104987-11-3
Purity:>98% Package:1g;10g;100g; 1kg;10kg;100kg - CB Index:58
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- Company Name:Zhenjiang Renzhi Biotechnology Co., Ltd.
- Tel: 18762678737
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CAS:104987-11-3
Purity:98% Package:1g/袋/ - CB Index:58
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- Company Name:Fujian Kerui Pharmaceutical Co., Ltd.
- Tel:+86-591-83309157; 18505919179
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CAS:104987-11-3
Purity:In House Standard Remarks:In House Standard (DMF、GMP) More... - CB Index:62
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- Company Name:Wuhan DingCheng Biochemical Co.Ltd
- Tel:13545255233 13545255233
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CAS:104987-11-3
Purity:>=99% Package:1kg;5kg;25kg Remarks:>=99% - CB Index:58
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- Company Name:Wuhan Juchengyuan Biotechnology Co., Ltd
- Tel:400-027-6007 18062142210
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CAS:104987-11-3
Purity:99% - CB Index:58
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