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Nizatidine

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76963-41-2 Basic informationMore
USE
Nizatidine, N-[2-[[[2-(dimethylamino)methyl]-4-thiazolyl]methyl]thio]-ethyl]-N'-methyl-2-nitro-1,1-ethenediamine (Axid), is an off-white to buff crystallinesolid that is soluble in water, alcohol, and chloroform. It isa thaizole derivative of raniditine and has pKas of 2.1 (side chain) and 6.8 (dimethylamino). Nizatidine’s mechanism ofaction is similar to other H<sub>2</sub>-antagonists, as is its receptor selectivity.It is more potent than cimetidine.<br/>Nizatidine has excellent oral bioavailability (>90%).The effects of antacids or food on its bioavailability arenot clinically significant. The elimination half-life is 1 to2 hours. It is excreted primarily in the urine (90%) andmostly as unchanged drug (60%). Metabolites include nizatidinesulfoxide (6%), N-desmethylnizatidine (7%), andnizatidine N-oxide (dimethylaminomethyl function).Nizatidine has no demonstrable antiandrogenic action, effectson other hormones, or inhibitory effects on cytochromeisozymes involved in the metabolism of other drugs.
Lastest Price from Nizatidine manufacturers
  • Nizatidine
  • US $0.00 /KG
  • CAS:76963-41-2
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • 2024-03-16
  • Nizatidine
  • US $1.00-1.00/Kg/Bag
  • CAS:76963-41-2
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
  • 2024-02-01

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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
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  • Company Name:Adamas Reagent, Ltd.
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