Tizanidine

• Product Name:Tizanidine
• Synonyms: 3-benzothiadiazole,5-chloro-4-(2-imidazolin-2-ylamino)-1 3-benzothiadiazole-4-amine,5-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-1 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole 5-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-2,1,3-BENZOTHIADIAZOLE-4-AMINE HYDROCHLORIDE 5-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-2,1,3-benzothiadiazole-4-amine (5-CHLORO-BENZO[1,2,5]THIADIAZOL-4-YL)-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-AMINE AB-021 DS-103-282
• CAS:51322-75-9
• MF:C9H8ClN5S
• MW:253.71
• EINECS:
• Mol File:51322-75-9.mol
• 

<ol> <li>In vitro studies of human liver microsomal cytochrome P450 isozymes showed that Tizanidine and its metabolites do not affect the metabolism of other enzymes.</li> <li>Tizanidine makes the peak time of acetaminophen delayed by 16 minutes, but paracetamol does not affect the pharmacokinetic parameters of Tizanidine.</li> <li>Ethanol increases the area under the curve of Tizanidine by 20%, resulting in an increase of 15% in the maximum peak concentration and an increased side effect in Tizanidine.The central nervous system inhibition of ethanol and Tizanidine has additive effect.</li> <li>4mg Tizanidine&rsquo;s single or repeated retrospective study showed that the use of oral contraceptives compared with patients who did not take oral contraceptives at the same time reduced the scavenging rate of Tizanidine Hydrochloride by 50%.</li> <li>When combined with antihypertensive drugs and diuretics, hypotension and bradycardia can be induced.</li> <li>It is prohibited to use combined with fluoxamine or ciprofloxacin(Cytochrome oxidase CYP1A2 inhibitor). Clinical studies showed that the pharmacokinetic parameters of Tizanidine (area under the curve, elimination half-life, maximum blood concentration, and oral bioavailability) will be increased when combined with fluoxamine and ciprofloxacin simultaneously, while the plasma clearance rate will be decreased. This pharmacokinetic interaction may lead to serious adverse events.</li> </ol>

• Tizanidine
• 
• US $50.00 /KG
• CAS:51322-75-9
• Min. Order: 1KG
• Purity: 99.9%
• Supply Ability: 500MT/month
• 2023-03-27

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Tizanidine
  CAS:51322-75-9
  Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
• CB Index:69
• Related Information:Catalog(15839)

• Company Name:Cangzhou Enke Pharma-tech Co., Ltd.
• Tel:0317-5296180 15533709196
• Products Intro:Product Name:Tizanidine
  CAS:51322-75-9
  Purity:99%化工级 沧州恩科医药科技，大量现货，优势产品，欢迎询价下单，随时为您服务！ Package:1kg;2kg;1212kg
• CB Index:55
• Related Information:Catalog(1898)

• Company Name:Beijing Solarbio Science & Tecnology Co., Ltd.
• Tel:010-50973130 4009686088
• Products Intro:CAS:51322-75-9
  
• CB Index:68
• Related Information:Catalog(29785)