Altretamine

• Product Name:Altretamine
• Synonyms: 2,4,6-Tris(dimethylamino)-1,3,5-triazine 96% 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl- 1,3,5-tris(dimethylamino)-s-triazine 2,4,6-tris(dimethylamino)-s-triazin 2,4,6-Tris(Dimethylamino)-s-triazine 5-triazine-2,4,6-triamine,n,n,n’,n’,n’’,n’’-hexamethyl-3 HEXAMETHYLMELAMINE Altretamine, >=99%
• CAS:645-05-6
• MF:C9H18N6
• MW:210.28
• EINECS:211-428-4
• Mol File:645-05-6.mol
• 

Altretamine is available in 50-mg capsules for oraladministration as a second-line treatment for ovarian cancer.The mechanism of action has not been firmly established, althoughthe spectrum of activity is similar to that for otheralkylating agents; however, cross-resistance is not seen.Cytotoxicity has been correlated with metabolism to give thecarbinolamines, which may form imines capable of crosslinking,or decompose to give formaldehyde, which may reactwith nucleophiles on DNA or proteins. The agent is well absorbedupon oral administration, well distributed, and highly(90%) plasma protein bound. The agent is extensively metabolizedin the liver by CYP to give demethylated metabolites via the previously mentioned carbinolamines. Elimination occursprimarily in the urine as mostly demethylated metaboliteswith a terminal elimination half-life of 4 to 10 hours.Myleosuppression and nausea/vomiting are dose-limitingtoxicities. Other adverse effects include lethargy, agitation,hallucinations, skin rash, and elevations in transaminase levels,flulike symptoms, abdominal cramps, and diarrhea.

• Altretamine
• 
• $2.00-5.00
• CAS:645-05-6
• Min. Order: 1KG
• Purity: 99% hplc
• Supply Ability: 500TONS
• 2025-05-07

• Altretamine
• 
• $10.00 /KG
• CAS:645-05-6
• Min. Order: 1KG
• Purity: 99%
• Supply Ability: 10 mt
• 2025-04-21

• Company Name:J & K SCIENTIFIC LTD.
• Tel:18210857532 18210857532
• Products Intro:Product Name:AltretaMine
  CAS:645-05-6
  Package:100Mg,10Mg More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:Nanjing Chemlin Chemical Co., Ltd
• Tel:025-83697070 13770331960
• Products Intro:Product Name:Altretamine
  CAS:645-05-6
  Purity:0.98 Package:5KG; 1KG More...
• CB Index:64
• Related Information:Catalog(16307)

• Company Name:Shanghai Hanhong Scientific Co.,Ltd.
• Tel:021-54306202 13764082696
• Products Intro:Product Name:ALTRETAMINE
  CAS:645-05-6
  Purity:0.97 Remarks:D61036 More...
• CB Index:64
• Related Information:Catalog(42917)

• Company Name:Chemsky（shanghai）International Co.,Ltd.
• Tel:021-50135380
• Products Intro:Product Name:AltretaMine
  CAS:645-05-6
  Purity:98% More...
• CB Index:50
• Related Information:Catalog(32273)

• Company Name:Syntechem Co.,Ltd
• Tel:
• Products Intro:Product Name:N2,N2,N4,N4,N6,N6-hexaMethyl-1,3,5-triazine-2,4,6-triaMine
  CAS:645-05-6
  Purity:97% Package:1g;5g;25g;100g;250g;1kg;5kg;10kg;25kg Remarks:we offer low price custom synthesis and contract manufacturing More...
• CB Index:57
• Related Information:Catalog(12973)

• Company Name:China Langchem Inc.
• Tel:0086-21-58956006
• Products Intro:Product Name:Altretamine
  CAS:645-05-6
  Purity:99% HPLC Package:10g;100G;1KG
• CB Index:57
• Related Information:Catalog(7798)

• Company Name:Sinopharm Chemical Reagent Co,Ltd.
• Tel:86-21-63210123
• Products Intro:Product Name:Altretamine (500 mg)
  CAS:645-05-6
  Package:500 mg More...
• CB Index:79
• Related Information:Catalog(9791)

• Company Name:Spectrum Chemical Manufacturing Corp.
• Tel:021-021-021-67601398-809-809-809 15221380277
• Products Intro:Product Name:AltretaMine, USP
  CAS:645-05-6
  Purity:USP Package:1KGBL Remarks:A3035 More...
• CB Index:60
• Related Information:Catalog(9643)