Letrozole

• Product Name:Letrozole
• Synonyms: Letrozole99% CGS-20267, Femara letrozolex Lelrozol 1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile 4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile 4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile
• CAS:112809-51-5
• MF:C17H11N5
• MW:285.3
• EINECS:675-034-8
• Mol File:112809-51-5.mol
• 

Letrozole, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)dibenzonitrile (Femara), is used for most of thesame indications as anastrozole. It reduces concentrations ofestrogens by 75% to 95%, with maximal suppressionachieved within 2 to 3 days. Letrozole is specific for aromataseinhibition, with no additional effects on adrenal corticoidbiosynthesis. CYPs 3A4 and 2A6 are involved in themetabolism of letrozole to the major carbinol metabolite,which is inactive. The loss of the triazole ring, which is involvedin coordination of the heme iron, would explain theloss of activity. Letrozole strongly inhibits CYP2A6 invitro, with moderate inhibition of CYP2C19. The effect ofthis in vitro inhibition on the pharmacokinetics of coadministereddrugs is unknown. Tamoxifen reduces the levels ofletrozole significantly if they are used together, so combinationtreatment with these agents is not recommended.

• Letrazole
• 
• US $850.00-650.00/g
• CAS:112809-51-5
• Min. Order: 10000g
• Purity: 99.9%
• Supply Ability: 100kg
• 2024-12-04

• Letrozole
• 
• US $0.00 /Kg/Bag
• CAS:112809-51-5
• Min. Order: 2Kg/Bag
• Purity: 99% up, High Density
• Supply Ability: 20 tons
• 2024-12-03

• Company Name:Jiangxi taisinor Co., Ltd.
• Tel: 13576915071
• Products Intro:Product Name:Letrozole
  CAS:112809-51-5
  Purity:HPLC>99.5% Package:500kg;25kg;1kg Remarks:USP
• CB Index:58
• Related Information:Catalog(27)

• Company Name:Hangzhou Lenny Technology Co. , Ltd.
• Tel:571-88086013
• Products Intro:Product Name:LETROZOLE
  Purity:USP，≥99% Package:100kg More...
• CB Index:60
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• Company Name:Jinan Kaypharm Chemical Co.,Ltd.
• Tel:0531-86986780 13153183025
• Products Intro:Product Name:letrozole
  CAS:112809-51-5
  Purity:99 Package:100 More...
• CB Index:55
• Related Information:Catalog(105)

• Company Name:Suzhou Unite pharmTech Co., Ltd ,
• Tel:792-3901125 13222993784
• Products Intro:Product Name:Letrozole
  CAS:112809-51-5
  Purity:99% HPLC Package:25k,5KG;1KG More...
• CB Index:56
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• Company Name:Nanjing Yunzhi Xinhe Biotechnology Co., Ltd
• Tel:19852363252; 19852363252
• Products Intro:Product Name:Letrozole
  CAS:112809-51-5
  Purity:HPLC99+ Package:500g；1kg；5kg;10kg;25kg
• CB Index:58
• Related Information:Catalog(53)

• Company Name:Jiangsu Xinglin Pharmaceutical Co., Ltd
• Tel: 18036652731
• Products Intro:Product Name:Letrozole
  CAS:112809-51-5
  Purity:99% Package:500g;1kg;100kg
• CB Index:58
• Related Information:Catalog(54)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Letrozole
  CAS:112809-51-5
  Remarks:C13811 More...
• CB Index:61
• Related Information:Catalog(6005)