Letrozole
112809-51-5 Basic informationMore
- Product Name:Letrozole
- Synonyms: Letrozole99% CGS-20267, Femara letrozolex Lelrozol 1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile 4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile 4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile
- CAS:112809-51-5
- MF:C17H11N5
- MW:285.3
- EINECS:675-034-8
- Mol File:112809-51-5.mol
-
USE
Letrozole, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)dibenzonitrile (Femara), is used for most of thesame indications as anastrozole. It reduces concentrations ofestrogens by 75% to 95%, with maximal suppressionachieved within 2 to 3 days. Letrozole is specific for aromataseinhibition, with no additional effects on adrenal corticoidbiosynthesis. CYPs 3A4 and 2A6 are involved in themetabolism of letrozole to the major carbinol metabolite,which is inactive. The loss of the triazole ring, which is involvedin coordination of the heme iron, would explain theloss of activity. Letrozole strongly inhibits CYP2A6 invitro, with moderate inhibition of CYP2C19. The effect ofthis in vitro inhibition on the pharmacokinetics of coadministereddrugs is unknown. Tamoxifen reduces the levels ofletrozole significantly if they are used together, so combinationtreatment with these agents is not recommended.
Lastest Price from Letrozole manufacturers
- Letrozole
-
- $1.00 /BOX
- CAS:112809-51-5
- Min. Order: 1BOX
- Purity: 99.6%
- Supply Ability: 1000000 BOX
- 2026-09-28
- Tamoxifen, or Nolvadex
-
- $21.00-23.00
- CAS:
- Min. Order: 1BOX
- Purity: 99.99%
- Supply Ability: 100000 BOX
- 2026-09-10
Browse by Nationality 112809-51-5 Suppliers >Global suppliers
Other (1) Beijing (33) Shanghai (102) Tianjin (4) Chongqing (5) Sichuan (16) Guangdong (54) Zhejiang (65) Fujian (11) Hunan (10) Hubei (69) Shandong (31) Shanxi (1) Henan (10) Hebei (21) Jilin (3) Liaoning (3) Heilongjiang (1) Anhui (9) Jiangsu (77) Jiangxi (2) Hainan (2) Shaanxi (15) Guangxi (1) Hong Kong (5) Taiwan (3) Other (3) Member (488) All (557)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Jiangxi taisinor Co., Ltd.
- Tel: 13576915071
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
Purity:HPLC>99.5% Package:500kg;25kg;1kg - CB Index:58
- Related Information:Catalog(80)
- Company Name:Hangzhou Lenny Technology Co. , Ltd.
- Tel:571-88086013
- Products Intro:Product Name:LETROZOLE
Purity:USP，≥99% Package:100kg More... - CB Index:60
- Related Information:Catalog(105)
- Company Name:Jinan Kaypharm Chemical Co.,Ltd.
- Tel:0531-86986780 13153183025;
- Products Intro:Product Name:letrozole
CAS:112809-51-5
Purity:99 Package:100 More... - CB Index:55
- Related Information:Catalog(108)
- Company Name:Jiujiang Yulite Pharmaceutical Technology Co., Ltd.
- Tel:792-3901125 13222993784
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
Purity:99% HPLC Package:25k;5KG;1KG More... - CB Index:56
- Related Information:Catalog(433)
- Company Name:Shandong Mingfeng Pharmaceutical and Technology Co. Ltd
- Tel:053155551677 15315114555
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
Purity:99% HPLC Package:5KG;1KG - CB Index:58
- Related Information:Catalog(298)
- Company Name:HANGZHOU DUHE CHEMICAL&TECHNOLOGY CO.,LTD
- Tel:0571-89905385 13858109112
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
Purity:99% HPLC Package:1kg;5kg;25kg - CB Index:58
- Related Information:Catalog(140)
- Company Name:Hubei Yuanmeng Biological Technology Co., Ltd.
- Tel:027-68897569 17740516530
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
Purity:99% Package:1KG/RMB 340;25KG/RMB 260 - CB Index:58
- Related Information:Catalog(2913)
- Company Name:Shanghai Boyle Chemical Co., Ltd.
- Tel: 021-50182298 021-50180596
- Products Intro:Product Name:Letrozole
CAS:112809-51-5
- CB Index:55
- Related Information:Catalog(2202)