OMecaMtiv Mecarbil
873697-71-3 Basic informationMore
- Product Name:OMecaMtiv Mecarbil
- Synonyms: 1-Piperazinecarboxylic acid,4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester OMecaMtiv Mecarbil OMecaMtiv Mecarbil (CK-1827452) CK1827452 CK-1827452 CK-1827452 (OMecaMtiv Mecarbil) CK 1827452O mecamtiv mecarbil
- CAS:873697-71-3
- MF:C20H24FN5O3
- MW:401.43
- EINECS:850-774-6
- Mol File:873697-71-3.mol
-
USE
Omecamtiv mecarbil significantly increases fractional shortening starting at 0.4 mM plasma concentrations in SD rats, sham animals and in rats with heart failure. In conscious dogs with myocardial infarction (MI-sHF), Omecamtiv mecarbil leads to a significant increase in wall thickening (25%), stroke volume (44%), cardiac output (22%) and left ventricular (LV) systolic ejection time (26%). In addition, Omecamtiv mecarbil also results in the decreases of some hemodynamic parameters including heart rate, mean left atrial pressure, and LV end-diastolic pressure. In conscious dogs with left ventricular hypertrophy (LVH-sHF), Omecamtiv mecarbil leads to similar and not statistically different effects on hemodynamic parameters.
Lastest Price from OMecaMtiv Mecarbil manufacturers
- Omecamtiv Mecarbil
-
- US $1.00 /KG
- CAS:873697-71-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000kg
- 2021-04-16
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:CK 1827452
CAS:873697-71-3
Package:100Mg,10Mg,50Mg,5Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:OMecaMtiv Mecarbil
CAS:873697-71-3
Purity:>98%,BR Package:50MG Remarks:4980 More... - CB Index:58
- Related Information:Catalog(4647)
- Company Name:Shanghai Topbiochem Technology Co., Ltd
- Tel:021-58170097
- Products Intro:Product Name:1-Piperazinecarboxylic acid,4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester
CAS:873697-71-3
Purity:98% Package:1g/1980;500mg/1180;100mg/480 - CB Index:58
- Related Information:Catalog(9442)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:18521735133 18521732826;
- Products Intro:Product Name:Omecamtiv mecarbil (CK-1827452)
CAS:873697-71-3
Purity:>=98% Package:10mg/RMB 1411.90;50mg/RMB 4999.90;5mg/RMB 824.90 More... - CB Index:65
- Related Information:Catalog(25015)