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89365-50-4 Basic informationMore
Antiasthmatic drugs are the drugs that can act on the different links of the asthma attack in order to relieve or prevent the attack of asthma.<br /> Salmeterol is a new long-acting beta 2 agonist antiasthmatic drug, derived from salbutamol, and closely linked to beta 2 receptor, resulting in more durable activation. Its chemical name is hydroxy naphthalate, which is white or white like powder with bitter taste. It was first developed by the British GlaxoSmithKline Co and was first listed in the UK in 1990.<br /> Its commodity name is Serevent, Salmeterol Xinafoate Aerosol,Sertindole and Salmeterol. It can inhibit the release of hypersensitivity mediators from the mast cells in the lung. It can inhibit the early and late phase reaction induced by inhalation antigen and reduce the hyperresponsiveness of the trachea. Clinical trials show that is salmeterol stronger than salbutamol. It has a longer duration effect to protect asthma caused by histamine induced bronchoconstriction and movement. It features long duration, small extrapulmonary effect and good tolerance. It is an ideal drug for the treatment of nocturnal attack and asthma. The pharmacokinetic study has indicated that this dose of this product twice a day, 50&mu;g each time. 5~15 min after 1 inhalation of 50 and 400&mu;g, the highest plasma concentration will be 0.1 to 0.2&mu;g /L and 1 ~ &mu;g/L respectively. This product is strongly metabolizing by hydrolysis, and most of the dosage is eliminated in 72h. The doses of 23% and 57% in 168h can be found in urine and feces respectively. In addition, salmeterol has a controlled effect on histamine, leukotrienes and prostaglandins. It is worth notice that this product can not be used with non selective beta blockers for the treatment of asthma, and it should be prudent for patients with asthma with heart disease. Salmeterol &#39;s common adverse reactions include hypokalemia, abnormal bronchospasm, tremor, headache, and palpitations. Its common beta agonists include: ephedrine, isoproterenol, salbutamol, terbutaline, clenbuterol, clorprenaline, tulobuterol, clenbuterol, procaterol, salmeterol, bambuterol, methoxyphenamine, rimiterol, bitolterol, sonarin, butero, fenoterol etc..
Lastest Price from Salmeterol manufacturers
  • Salmeterol
  • US $0.00 /KG
  • CAS:89365-50-4
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • 2021-06-11
  • Salmeterol USP/EP/BP
  • US $1.10 /g
  • CAS:89365-50-4
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • 2021-05-28

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  • Company Name:Bono Kangyuan (Beijing) Pharmaceutical Technology Co., Ltd
  • Tel:18518759099 01056380788-8515
  • Products Intro:Product Name:Salmeterol
    Purity:99% HPLC Package:500g;1kg(可根据客户要求包装)
  • CB Index:58
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Products Intro:Product Name:SalMeterol;4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]aMino]Methyl]-1,3-benzenediMethanol
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456-
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    Remarks:C14138 More...
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  • Company Name:Shanghai Longsheng chemical Co.,Ltd.
  • Tel:13585536065 021-58099652-8005
  • Products Intro:Product Name:Salmeterol
    Purity:98% Package:5g;25g;100g;1kg;5kg;10kg;100kg More...
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  • Company Name:Nanjing Chemlin Chemical Co., Ltd
  • Tel:025-83697070
  • Products Intro:Product Name:SalMeterol
    Purity:95%. Package:5g;1kg;10kg More...
  • CB Index:64
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  • Company Name:Wuhan Sunrise Technology Development Co., Ltd.
  • Tel:13554138826
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